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ARL8A/ARL8B Monoclonal antibody, PBS Only

ARL8A/ARL8B Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2F4C3

Cat no : 68186-1-PBS

Print datasheet

Synonyms

ARL10B, ARL8A, FLJ45195, GIE2

验证数据展示

  • WB analysis using 68186-1-Ig (same clone as 68186-1-PBS)

    WB analysis using 68186-1-Ig (same clone as 68186-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68186-1-Ig (ARL8A/ARL8B antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68186-1-PBS in a different storage buffer formulation.

  • WB analysis using 68186-1-Ig (same clone as 68186-1-PBS)

    WB analysis using 68186-1-Ig (same clone as 68186-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68186-1-Ig (ARL8A/ARL8B antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68186-1-PBS in a different storage buffer formulation.

  • WB analysis using 68186-1-Ig (same clone as 68186-1-PBS)

    WB analysis using 68186-1-Ig (same clone as 68186-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68186-1-Ig (ARL8A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68186-1-PBS in a different storage buffer formulation.

产品信息

68186-1-PBS targets ARL8A/ARL8B in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, rabbit
Immunogen ARL8A/ARL8B fusion protein Ag10758 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name ADP-ribosylation factor-like 8A
Synonyms ARL10B, ARL8A, FLJ45195, GIE2
Calculated Molecular Weight 186 aa, 21 kDa
Observed Molecular Weight18 kDa, 21 kDa
GenBank Accession NumberBC015408
Gene Symbol ARL8A
Gene ID (NCBI) 127829
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96BM9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ARL8A (ADP-ribosylation factor-like protein 8A) is also named as ARL10B, GIE2 and belongs to the small GTPase superfamily. ARL8A is localized to lysosomes in mammalian cells (PMID: 16537643). In neurons, ARL8A mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles that are required for presynaptic biogenesis and synaptic function. ARL8A is upregulated in many cancers such as endometrial cancer (PMID: 32070877), colorectal cancer (PMID: 30546056) and inflammatory breast cancer (PMID: 27648361), and has been associated with poor survival outcomes. ARL8A/ARL8B can be recognized by this antibody.