ASAH1 Monoclonal antibody, PBS Only
ASAH1 Monoclonal Antibody for WB,Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, Pig, Rat, Rabbit
Applications
WB,Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2B3C7
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy ASAH1 Ready-To-Use IHC Kit. ASAH1 primary antibody included.
产品信息
67092-2-PBS targets ASAH1 in WB, Indirect ELISA applications and shows reactivity with Human, Pig, Rat, Rabbit samples.
Tested Applications | WB,Indirect ELISA Application Description |
Tested Reactivity | Human, Pig, Rat, Rabbit |
Immunogen | ASAH1 fusion protein Ag28645 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
Synonyms | AC, Acid ceramidase, Acylsphingosine deacylase, ASAH, ASAH1, FLJ21558, FLJ22079, HSD 33, PHP, PHP32, Putative 32 kDa heart protein |
Calculated Molecular Weight | 44 kDa |
Observed Molecular Weight | 44-55 kDa |
GenBank Accession Number | BC016828 |
Gene Symbol | ASAH1 |
Gene ID (NCBI) | 427 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q13510 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
背景介绍
ASAH1, also named as AC, ACDase, Acid CDase, PHP32 and ASAH, belongs to the acid ceramidase family. ASAH1 is a lipid hydrolase that catalyzes the conversion of ceramide (cer) into sphingosine (SPH) and a free fatty acid. Mutation of ASAH1 will cause the Farber lipogranulomatosis (FL) which also known as Farber disease (FD). ASAH1 is highly expressed in Heart. And it is first synthesized as an 55-60 kDa precursor and subsequently processed to the mature, heterodimeric enzyme (40 + 13 kDa) in the endosomes/lysosomes.