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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 67692-1-Ig (same clone as 67692-1-PBS)

    WB analysis using 67692-1-Ig (same clone as 67692-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67692-1-Ig (ASL antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67692-1-PBS in a different storage buffer formulation.

  • WB analysis of LNCaP using 67692-1-Ig (same clone as 67692-1-PBS)

    WB analysis of LNCaP using 67692-1-Ig (same clone as 67692-1-PBS)

    LNCaP cells were subjected to SDS PAGE followed by western blot with 67692-1-Ig (ASL antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67692-1-PBS in a different storage buffer formulation.

  • WB analysis of K-562 using 67692-1-Ig (same clone as 67692-1-PBS)

    WB analysis of K-562 using 67692-1-Ig (same clone as 67692-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67692-1-Ig (ASL antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67692-1-PBS in a different storage buffer formulation.

ASL Monoclonal antibody, PBS Only

ASL Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67692-1-PBS

产品说明书

CloneNo. 1G9H3

宿主/亚型

Mouse / IgG2b

种属反应性

Human, mouse, rat, pig

应用

WB, Indirect ELISA

别名

argininosuccinate lyase, Arginosuccinase, ASAL, ASL

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67692-1-PBS targets ASL in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat, pig
免疫原 ASL fusion protein Ag30517 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 argininosuccinate lyase
别名 argininosuccinate lyase, Arginosuccinase, ASAL, ASL
计算分子量 55 kDa
观测分子量50 kDa
GenBank蛋白编号BC008195
基因名称 ASL
Gene ID (NCBI) 435
RRIDAB_2882885
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP04424
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Argininosuccinate lyase (ASL), one of the significant UC enzymes, catalyzes argininosuccinate cleavage to generate arginine and fumarate. Arginine is then catalyzed by arginase to ornithine and polyamines, which are found to promote cancer cell proliferation and growth. Importantly, ASL ectopic expression is closely associated with poor prognosis of colorectal cancer, hepatocellular. ASL is a member of the aspartase/fumarase superfamily. Enzymes of this superfamily share similar tetrameric structure and active site, though the sequence identities between different members are quite low (less than 20%). Members of this superfamily have been recognised as drug targets for microbial infections. ASL is a 464-amino-acid enzyme with a molecular mass of 49.7 kDa. (PMID: 22386318 PMID: 31018905)