• 概述
  • 经过测试的应用
  • 产品信息

ATP8A2 Polyclonal antibody, PBS Only

ATP8A2 Polyclonal Antibody for IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 31697-1-PBS

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Synonyms



产品信息

31697-1-PBS targets ATP8A2 in IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen ATP8A2 fusion protein Ag36276 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
Synonyms
Calculated Molecular Weight133kDa
Observed Molecular Weight129 kDa
GenBank Accession NumberNM_001313741
Gene Symbol ATP8A2
Gene ID (NCBI) 51761
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
UNIPROT IDQ9NTI2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ATP8A2 is also known as ATPIB. ATP8A2 is a member of the P4‐ATPase subfamily of P‐type ATPases that actively flips phosphatidylserine (PS) and phosphatidylethanolamine (PE) across membranes to generate and maintain transmembrane phospholipid asymmetry, a property important in such cellular processes as vesicle trafficking, apoptosis, cytokinesis, neuron survival, blood coagulation, and phagocytosis. ATP8A2 consists of an N‐domain involved in binding ATP, a P‐domain that undergoes phosphorylation, an A‐domain that functions in the dephosphorylation of the phosphorylated intermediate, and an M‐domain consisting of 10 transmembrane segments that comprise the pathway for translocation of the lipid across the membrane. ATP8A2 is highly expressed in the brain, spinal cord, testis, and retina (PMID: 33565221, PMID: 33766557, PMID: 37635783).