AXL Monoclonal antibody

AXL Monoclonal Antibody for WB, ELISA
Cat No. 68108-1-Ig

产品说明书

CloneNo. 3D12F11

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, ELISA

UFO, Tyrosine-protein kinase receptor UFO, EC:2.7.10.1, 3D12F11

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inNCI-H1299 cells, A549 cells, U2OS cells, A431 cells, HeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

68108-1-Ig targets AXL in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 AXL fusion protein Ag14401 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 AXL receptor tyrosine kinase
别名 UFO, Tyrosine-protein kinase receptor UFO, EC:2.7.10.1, 3D12F11
计算分子量 894 aa, 98 kDa
观测分子量130-140 kDa
GenBank蛋白编号BC032229
基因名称 AXL
Gene ID (NCBI) 558
RRIDAB_2923637
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP30530
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Axl, also known as Ufo or Ark, is a receptor tyrosine kinase of the TAM (Tyro3, Axl and Mer) family. Axl is a single-pass type I membrane protein containing two fibronectin type-III domains, two Ig-like C2-type domains and one protein kinase domain. Axl mRNA is widely expressed with highest levels in the heart and skeletal muscle. Gas6 has been identified as a ligand for human Axl. Gas6/Axl signaling plays a role in cell survival, cell proliferation, migration and differentiation. It has been reported that 110-120 kDa non-glycosylated AXL protein can be detected(PMID: 31171001). Endogenous Axl is auto-phosphorylated and reacted with a tyrosine-phosphorylated protein of 140 kDa(PMID: 12730092).

实验方案

Product Specific Protocols
WB protocol for AXL antibody 68108-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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