AXL Monoclonal antibody, PBS Only

AXL Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68108-1-PBS

产品说明书

CloneNo. 3D12F11

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Indirect ELISA

UFO, Tyrosine-protein kinase receptor UFO, EC:2.7.10.1, 3D12F11

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

68108-1-PBS targets AXL in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 AXL fusion protein Ag14401 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 AXL receptor tyrosine kinase
别名 UFO, Tyrosine-protein kinase receptor UFO, EC:2.7.10.1, 3D12F11
计算分子量 894 aa, 98 kDa
观测分子量130-140 kDa
GenBank蛋白编号BC032229
基因名称 AXL
Gene ID (NCBI) 558
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP30530
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Axl, also known as Ufo or Ark, is a receptor tyrosine kinase of the TAM (Tyro3, Axl and Mer) family. Axl is a single-pass type I membrane protein containing two fibronectin type-III domains, two Ig-like C2-type domains and one protein kinase domain. Axl mRNA is widely expressed with highest levels in the heart and skeletal muscle. Gas6 has been identified as a ligand for human Axl. Gas6/Axl signaling plays a role in cell survival, cell proliferation, migration and differentiation. It has been reported that 110-120 kDa non-glycosylated AXL protein can be detected(PMID: 31171001). Endogenous Axl is auto-phosphorylated and reacted with a tyrosine-phosphorylated protein of 140 kDa(PMID: 12730092).

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