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  • Featured Product
  • KD/KO Validated

Adiponectin receptor 1 Monoclonal antibody, PBS Only

Adiponectin receptor 1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F12B3

Cat No : 66619-1-PBS

Print datasheet

Synonyms

ACDCR1, Adiponectin receptor 1, Adiponectin receptor protein 1, ADIPOR1, CGI 45, CGI45, PAQR1, TESBP1A

验证数据展示

  • WB analysis of HEK-293 using 66619-1-Ig (same clone as 66619-1-PBS)

    WB analysis of HEK-293 using 66619-1-Ig (same clone as 66619-1-PBS)

    WB result of Adiponectin receptor 1 antibody (66619-1-Ig; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Adiponectin receptor 1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66619-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 66619-1-Ig (same clone as 66619-1-PBS)

    WB analysis of HeLa using 66619-1-Ig (same clone as 66619-1-PBS)

    HeLa cells, L02 cells, and HepG2 cells were subjected to SDS PAGE followed by western blot with 66619-1-Ig (Adiponectin receptor 1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66619-1-PBS in a different storage buffer formulation.

产品信息

66619-1-PBS targets Adiponectin receptor 1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen Adiponectin receptor 1 fusion protein Ag18187 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name adiponectin receptor 1
Synonyms ACDCR1, Adiponectin receptor 1, Adiponectin receptor protein 1, ADIPOR1, CGI 45, CGI45, PAQR1, TESBP1A
Calculated Molecular Weight 375 aa, 43 kDa
Observed Molecular Weight 43 kDa
GenBank Accession NumberBC010743
Gene Symbol ADIPOR1
Gene ID (NCBI) 51094
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ96A54
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin have been identified: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). They are seven-transmembrane domain receptors and mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is found in many tissues, being particularly abundant in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver (PMID: 24417942). AdipoR1 has a high affinity for globular adiponectin and a very low affinity for full-length adiponectin. AdipoR2 has an intermediate affinity for both forms. The human ADIPOR1 gene maps to chromosome 1q32.1, and encodes a 375-amino acid protein with a molecular weight of 43 kDa. This antibody was raised against 1-72aa of human AdipoR1.