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验证数据展示

  • WB analysis of HEK-293 using 66619-1-Ig (same clone as 66619-1-PBS)

    WB analysis of HEK-293 using 66619-1-Ig (same clone as 66619-1-PBS)

    WB result of Adiponectin receptor 1 antibody (66619-1-Ig; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Adiponectin receptor 1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66619-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 66619-1-Ig (same clone as 66619-1-PBS)

    WB analysis of HeLa using 66619-1-Ig (same clone as 66619-1-PBS)

    HeLa cells, L02 cells, and HepG2 cells were subjected to SDS PAGE followed by western blot with 66619-1-Ig (Adiponectin receptor 1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66619-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

Adiponectin receptor 1 Monoclonal antibody, PBS Only

Adiponectin receptor 1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66619-1-PBS

产品说明书

CloneNo. 1F12B3

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, Indirect ELISA

别名

ACDCR1, Adiponectin receptor 1, Adiponectin receptor protein 1, ADIPOR1, CGI 45, CGI45, PAQR1, TESBP1A

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66619-1-PBS targets Adiponectin receptor 1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 Adiponectin receptor 1 fusion protein Ag18187 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 adiponectin receptor 1
别名 ACDCR1, Adiponectin receptor 1, Adiponectin receptor protein 1, ADIPOR1, CGI 45, CGI45, PAQR1, TESBP1A
计算分子量 375 aa, 43 kDa
观测分子量 43 kDa
GenBank蛋白编号BC010743
基因名称 Adiponectin receptor 1
Gene ID (NCBI) 51094
RRIDAB_2881979
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ96A54
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin have been identified: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). They are seven-transmembrane domain receptors and mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is found in many tissues, being particularly abundant in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver (PMID: 24417942). AdipoR1 has a high affinity for globular adiponectin and a very low affinity for full-length adiponectin. AdipoR2 has an intermediate affinity for both forms. The human ADIPOR1 gene maps to chromosome 1q32.1, and encodes a 375-amino acid protein with a molecular weight of 43 kDa. This antibody was raised against 1-72aa of human AdipoR1.