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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis of human plasma using 66078-1-Ig (same clone as 66078-1-PBS)

    WB analysis of human plasma using 66078-1-Ig (same clone as 66078-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 66078-1-Ig (Alpha Antichymotrypsin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66078-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66078-1-Ig (same clone as 66078-1-PBS)

    IHC staining of human tonsillitis using 66078-1-Ig (same clone as 66078-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66078-1-Ig (alpha 1 Antichymotrypsin antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66078-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SERPINA3/AACT antibody included
  • IHC staining of human tonsillitis using 66078-1-Ig (same clone as 66078-1-PBS)

    IHC staining of human tonsillitis using 66078-1-Ig (same clone as 66078-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66078-1-Ig (alpha 1 Antichymotrypsin antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66078-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SERPINA3/AACT antibody included
  • IF Staining of human tonsillitis using 66078-1-Ig (same clone as 66078-1-PBS)

    IF Staining of human tonsillitis using 66078-1-Ig (same clone as 66078-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using 66078-1-Ig (alpha 1 Antichymotrypsin antibody) at dilution of 1:100 and CoraLite488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66078-1-PBS in a different storage buffer formulation.

Alpha 1 antichymotrypsin Monoclonal antibody, PBS Only

Alpha 1 antichymotrypsin Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 66078-1-PBS

产品说明书

CloneNo. 3F2F10

宿主/亚型

Mouse / IgG2b

种属反应性

human, pig

应用

WB, IHC, IF-P, Indirect ELISA

别名

Alpha Antichymotrypsin, SERPINA3, ACT, AACT, A-1-Antichymotrypsin

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy SERPINA3/AACT Ready-To-Use IHC Kit. SERPINA3/AACT primary antibody included.

产品信息

66078-1-PBS targets Alpha 1 antichymotrypsin in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, pig
免疫原 Alpha 1 antichymotrypsin fusion protein Ag2830 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
别名 Alpha Antichymotrypsin, SERPINA3, ACT, AACT, A-1-Antichymotrypsin
计算分子量 448 aa, 48 kDa
观测分子量 60 kDa
GenBank蛋白编号BC010530
基因名称 Alpha 1 Antichymotrypsin
Gene ID (NCBI) 12
RRIDAB_11182502
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP01011
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.