验证数据展示
产品信息
68086-1-PBS targets Annexin VI in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with rabbit, pig, rat, mouse, human samples.
Tested Applications | WB, IF/ICC, FC (Intra), Indirect ELISA Application Description |
Tested Reactivity | rabbit, pig, rat, mouse, human |
Immunogen | Annexin VI fusion protein Ag3263 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | annexin A6 |
Synonyms | Annexin A6, ANXA6, ANX6, Annexin-6, Annexin 6 |
Calculated Molecular Weight | 673 aa, 76 kDa |
Observed Molecular Weight | 67 kDa |
GenBank Accession Number | BC017046 |
Gene Symbol | Annexin VI |
Gene ID (NCBI) | 309 |
RRID | AB_2918823 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P08133 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ANXA6, also called CBP68, or 67 kDa calelectrin, belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.