验证数据展示
产品信息
68086-1-PBS targets Annexin VI in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with rabbit, pig, rat, mouse, human samples.
经测试应用 | WB, IF/ICC, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | rabbit, pig, rat, mouse, human |
免疫原 | Annexin VI fusion protein Ag3263 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | annexin A6 |
别名 | Annexin A6, ANXA6, ANX6, Annexin-6, Annexin 6 |
计算分子量 | 673 aa, 76 kDa |
观测分子量 | 67 kDa |
GenBank蛋白编号 | BC017046 |
基因名称 | Annexin VI |
Gene ID (NCBI) | 309 |
RRID | AB_2918823 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P08133 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ANXA6, also called CBP68, or 67 kDa calelectrin, belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.