验证数据展示
产品信息
67326-1-PBS targets Arp5/ACTR5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse, rat, pig |
Immunogen | Arp5/ACTR5 fusion protein Ag15976 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | ARP5 actin-related protein 5 homolog (yeast) |
Synonyms | Actin related protein 5, ACTR5, Arp5, Arp5/ACTR5, FLJ12785, hARP5, INO80M, Sarcoma antigen NY SAR 16 |
Calculated Molecular Weight | 607 aa, 68 kDa |
Observed Molecular Weight | 68 kDa |
GenBank Accession Number | BC038402 |
Gene Symbol | ARP5/ACTR5 |
Gene ID (NCBI) | 79913 |
RRID | AB_2882585 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9H9F9 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Arp5 is a member of nuclear actin-related proteins (ARPs) that function as components of the chromatin- remodeling complex. Recently study reported that Arp5 regulates smooth muscle cell differentiation through interaction with myocardin (Myocd). Arp5 has been identified as negative regulator of Myocd, suppressing Myocd activity in the nucleus through tightly binding with Myocd RPEL motifs. Alternative splicing results in two variants of Arp5: a broadly expressed arp5-common, and a smooth muscle restricted arp5-sm. Expression of Arp5-sm protein is strongly suppressed in well-differentiated smooth muscle cells by partial messenger RNA decay and translational suppression. (24567363)