验证数据展示
产品信息
67326-1-PBS targets Arp5/ACTR5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat, pig |
免疫原 | Arp5/ACTR5 fusion protein Ag15976 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | ARP5 actin-related protein 5 homolog (yeast) |
别名 | Actin related protein 5, ACTR5, Arp5, Arp5/ACTR5, FLJ12785, hARP5, INO80M, Sarcoma antigen NY SAR 16 |
计算分子量 | 607 aa, 68 kDa |
观测分子量 | 68 kDa |
GenBank蛋白编号 | BC038402 |
基因名称 | ARP5/ACTR5 |
Gene ID (NCBI) | 79913 |
RRID | AB_2882585 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q9H9F9 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Arp5 is a member of nuclear actin-related proteins (ARPs) that function as components of the chromatin- remodeling complex. Recently study reported that Arp5 regulates smooth muscle cell differentiation through interaction with myocardin (Myocd). Arp5 has been identified as negative regulator of Myocd, suppressing Myocd activity in the nucleus through tightly binding with Myocd RPEL motifs. Alternative splicing results in two variants of Arp5: a broadly expressed arp5-common, and a smooth muscle restricted arp5-sm. Expression of Arp5-sm protein is strongly suppressed in well-differentiated smooth muscle cells by partial messenger RNA decay and translational suppression. (24567363)