• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse peritoneal macrophages using 65221-1-Ig (same clone as 65221-1-PBS)

    FC experiment of mouse peritoneal macrophages using 65221-1-Ig (same clone as 65221-1-PBS)

    1X10^6 mouse peritoneal macrophages were surface stained with 1 ug Anti-Mouse CD276 (65221-1-Ig, Clone:MJ18) and FITC anti-rat IgG1 Antibody at dilution 1:100 (red), or unstained (blue). Cells were not fixed. This data was developed using the same antibody clone with 65221-1-PBS in a different storage buffer formulation.

Anti-Mouse B7-H3/CD276 (MJ18), PBS Only

B7-H3/CD276 Monoclonal Antibody for FC
Cat No. 65221-1-PBS

Print datasheet

CloneNo. MJ18

Host / Isotype

Rat / IgG1, kappa

Reactivity

mouse

Applications

FC

Synonyms

Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

65221-1-PBS targets B7-H3/CD276 in FC applications and shows reactivity with mouse samples.

Tested Applications FC Application Description
Tested Reactivity mouse
Immunogen Mouse IgG2a Fc-CD276 (aa 1-242) fusion protein 种属同源性预测
Host / Isotype Rat / IgG1, kappa
Class Monoclonal
Type Antibody
Full Name CD276 antigen
Synonyms Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3
GenBank Accession NumberBC019436
Gene Symbol Cd276
Gene ID (NCBI) 102657
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ8VE98
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).