CoraLite®594 Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody

B7-H3/CD276 Uni-rAbTM Recombinant Antibody for FC
Cat No. CL594-98017

产品说明书

CloneNo. 230305A10

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

CD276, B7-H3, B7H3, B7 homolog 3, B7 H3

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inhuman monocyte-derived immature dendritic cells
For other applications, we recommend the unconjugated version of this antibody, 98017-1-PBS

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-98017 targets B7-H3/CD276 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD276 molecule
别名 CD276, B7-H3, B7H3, B7 homolog 3, B7 H3
计算分子量57 kDa
GenBank蛋白编号NM_001024736
基因名称 CD276
Gene ID (NCBI) 80381
RRIDAB_3673538
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ5ZPR3
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).

实验方案

Product Specific Protocols
FC protocol for CL594 B7-H3/CD276 antibody CL594-98017Download protocol
Standard Protocols
Click here to view our Standard Protocols
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