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Species Reactivity
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验证数据展示

  • IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MKKS antibody included
  • IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MKKS antibody included
  • IF Staining of hTERT-RPE1 cells using 13078-1-AP (same clone as 13078-1-PBS)

    IF Staining of hTERT-RPE1 cells using 13078-1-AP (same clone as 13078-1-PBS)

    IF result (cytoplasm and the base of cilia stain) of anti-BBS6 (13078-1-AP; 1:50) with hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    WB analysis of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 13078-1-AP (BBS6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

BBS6 Polyclonal antibody, PBS Only

BBS6 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 13078-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy MKKS Ready-To-Use IHC Kit. MKKS primary antibody included.

产品信息

13078-1-PBS targets BBS6 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 BBS6 fusion protein Ag3785 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 McKusick-Kaufman syndrome
别名
计算分子量 62 kDa
观测分子量 63 kDa
GenBank蛋白编号BC028973
基因名称 MKKS
Gene ID (NCBI) 8195
RRIDAB_10603370
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NPJ1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MKKS also known as BBS6 is a probable chaperone given to the amino acid similarity to the chaperonin family of proteins and may play a role in protein processing in limb, cardiac and reproductive system development. The mutations in BBS6 have been linked to Bardet-Biedl syndrome (BBS) which is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. It may also get involved in cellular organization processes, in particular relating to ciliary/flagellar and centrosomal activities.