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BBS6 Polyclonal antibody, PBS Only

BBS6 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13078-1-PBS

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Synonyms

验证数据展示

  • IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MKKS antibody included
  • IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with MKKS antibody included
  • IF Staining of hTERT-RPE1 cells using 13078-1-AP (same clone as 13078-1-PBS)

    IF Staining of hTERT-RPE1 cells using 13078-1-AP (same clone as 13078-1-PBS)

    IF result (cytoplasm and the base of cilia stain) of anti-BBS6 (13078-1-AP; 1:50) with hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    WB analysis of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 13078-1-AP (BBS6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy MKKS Ready-To-Use IHC Kit. MKKS primary antibody included.

产品信息

13078-1-PBS targets BBS6 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen BBS6 fusion protein Ag3785 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name McKusick-Kaufman syndrome
Synonyms
Calculated Molecular Weight 62 kDa
Observed Molecular Weight 63 kDa
GenBank Accession NumberBC028973
Gene Symbol MKKS
Gene ID (NCBI) 8195
RRIDAB_10603370
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NPJ1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MKKS also known as BBS6 is a probable chaperone given to the amino acid similarity to the chaperonin family of proteins and may play a role in protein processing in limb, cardiac and reproductive system development. The mutations in BBS6 have been linked to Bardet-Biedl syndrome (BBS) which is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. It may also get involved in cellular organization processes, in particular relating to ciliary/flagellar and centrosomal activities.