BCAM Recombinant antibody, PBS Only

BCAM Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84038-3-PBS

产品说明书

CloneNo. 241051C8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

F8/G253 antigen, CD239, B-CAM cell surface glycoprotein, Basal cell adhesion molecule, Auberger B antigen

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

84038-3-PBS targets BCAM in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 BCAM fusion protein Ag28181 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 basal cell adhesion molecule (Lutheran blood group)
别名 F8/G253 antigen, CD239, B-CAM cell surface glycoprotein, Basal cell adhesion molecule, Auberger B antigen
计算分子量 67 kDa
观测分子量67 kDa, 78-85 kDa
GenBank蛋白编号BC050450
基因名称 BCAM
Gene ID (NCBI) 4059
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP50895
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Basal cell adhesion molecule (Lu/BCAM) is a membrane-bound glycoprotein of the immunoglobulin superfamily (IgSF), functioning as a receptor for the extracellular matrix protein, laminin. BCAM (Lutheran/basal cell-adhesion molecule, a glycoprotein) belongs to the immunoglobulin superfamily which contains both Lu blood group and BCAM tumor-associated antigens. Proteomics analysis suggests that BCAM might be a potential biomarker for pancreatic cancer (PMID: 19199705). BCAM, involved in cell adhesion and migration, can also promote tumor metastasis and has been elucidated to play a functional role in the metastasis of thyroid cancer and gastric cancer (PMID: 10728810, 35941663). De-glycosylated BCAM has a preidicted molecular weight of 67 kDa. Two BCAM glycoprotein (gp) isoforms are present on human RBCs, Lu (85 kDa) and Lu(v13) (78 kDa); they result from the alternative splicing of intron 13 and differ by the lengths of their cytoplasmic domains (PMID: 23160466).

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