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  • Featured Product
  • KD/KO Validated

BCR Polyclonal antibody, PBS Only

BCR Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, monkey

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22585-1-PBS

Print datasheet

Synonyms

Renal carcinoma antigen NY-REN-26, EC:2.7.11.1, breakpoint cluster region, BCR1, BCR 1

验证数据展示

  • WB analysis of Y79 using 22585-1-AP (same clone as 22585-1-PBS)

    WB analysis of Y79 using 22585-1-AP (same clone as 22585-1-PBS)

    Y79 cells were subjected to SDS PAGE followed by western blot with 22585-1-AP (BCR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22585-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin using 22585-1-AP (same clone as 22585-1-PBS)

    IHC staining of human skin using 22585-1-AP (same clone as 22585-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin slide using 22585-1-AP (BCR Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 22585-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCR antibody included
  • IHC staining of human skin using 22585-1-AP (same clone as 22585-1-PBS)

    IHC staining of human skin using 22585-1-AP (same clone as 22585-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin slide using 22585-1-AP (BCR Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 22585-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BCR antibody included
  • IP experiment of HEK-293 using 22585-1-AP (same clone as 22585-1-PBS)

    IP experiment of HEK-293 using 22585-1-AP (same clone as 22585-1-PBS)

    IP result of anti-BCR (IP:22585-1-AP, 4ug; Detection:22585-1-AP 1:1000) with HEK-293 cells lysate 3000ug. This data was developed using the same antibody clone with 22585-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 22585-1-AP (same clone as 22585-1-PBS)

    IF Staining of HeLa using 22585-1-AP (same clone as 22585-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using BCR antibody (22585-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 22585-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy BCR Ready-To-Use IHC Kit. BCR primary antibody included.

产品信息

22585-1-PBS targets BCR in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, monkey samples.

Tested Applications WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
Tested Reactivity human, monkey
Immunogen BCR fusion protein Ag18281 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name breakpoint cluster region
Synonyms Renal carcinoma antigen NY-REN-26, EC:2.7.11.1, breakpoint cluster region, BCR1, BCR 1
Calculated Molecular Weight 143 kDa
Observed Molecular Weight 150-160 kDa
GenBank Accession NumberBC066122
Gene Symbol BCR
Gene ID (NCBI) 613
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDP11274
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. The Bcr gene encodes for the break point cluster region protein(Bcr). Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.