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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68435-1-Ig (same clone as 68435-1-PBS)

    WB analysis using 68435-1-Ig (same clone as 68435-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68435-1-Ig (BHLHE40 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68435-1-PBS in a different storage buffer formulation.

BHLHE40 Monoclonal antibody, PBS Only

BHLHE40 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68435-1-PBS
CloneNo. 1A3E1

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Synonyms

BHLHB2, BHLHE40, DEC1, FLJ99214, SHARP 2, SHARP2, STRA13, Stra14

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

68435-1-PBS targets BHLHE40 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen BHLHE40 fusion protein Ag12236 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name basic helix-loop-helix family, member e40
Synonyms BHLHB2, BHLHE40, DEC1, FLJ99214, SHARP 2, SHARP2, STRA13, Stra14
Calculated Molecular Weight 412 aa, 46 kDa
Observed Molecular Weight 46-50 kDa
GenBank Accession NumberBC082238
Gene Symbol BHLHE40
Gene ID (NCBI) 8553
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO14503
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BHLHE40 (Basic Helix-Loop-Helix Family Member E40), also known as BHLHB2, STRA13, DEC1, or SHARP2, is a member of the basic helix-loop-helix (bHLH) protein family, a large superfamily of transcriptional regulators expressed in many organisms. BHLHE40 is known to regulate a wide variety of essential cellular processes, including cell cycle, cellular proliferation, programmed cell death, cellular development and differentiation, as well as circadian rhythms (PMID: 34551158). It is reported that BHLHE40 is overexpressed in gastric, breast, and brain tumors; and downregulated in colorectal, esophageal, pancreatic and lung cancer (PMID: 32577154).