验证数据展示
经过测试的应用
| Positive WB detected in | pig lung tissue, pig liver tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
66370-1-Ig targets BMP5 in WB, ELISA applications and shows reactivity with human, pig samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, pig |
| 免疫原 | BMP5 fusion protein Ag3952 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | bone morphogenetic protein 5 |
| 别名 | BMP 5, BMP5, bone morphogenetic protein 5 |
| 计算分子量 | 454 aa, 52 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC027958 |
| 基因名称 | BMP5 |
| Gene ID (NCBI) | 653 |
| RRID | AB_2881749 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P22003 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Bone morphogenetic protein-5 (BMP5), is a member of the TGF-beta superfamily. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. BMP5 may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. BMP5 is differentially regulated in multiple human cancers.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for BMP5 antibody 66370-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
