验证数据展示
产品信息
66370-1-PBS targets BMP5 in WB, Indirect ELISA applications and shows reactivity with human, pig samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, pig |
免疫原 | BMP5 fusion protein Ag3952 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | bone morphogenetic protein 5 |
别名 | BMP 5, BMP5, BMP-5, bone morphogenetic protein 5 |
计算分子量 | 454 aa, 52 kDa |
观测分子量 | 52 kDa |
GenBank蛋白编号 | BC027958 |
基因名称 | BMP5 |
Gene ID (NCBI) | 653 |
RRID | AB_2881749 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P22003 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Bone morphogenetic protein-5 (BMP5), is a member of the TGF-beta superfamily. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. BMP5 may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. BMP5 is differentially regulated in multiple human cancers.