验证数据展示
产品信息
68497-1-PBS targets BMPR2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse |
免疫原 | BMPR2 fusion protein Ag5868 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
别名 | BMP type 2 receptor, BMP type II receptor, BMPR 2, BMPR II, BMPR2, BMPR3, BMR2, BRK 3, FLJ41585, FLJ76945, PPH1, T ALK |
计算分子量 | 115 kDa |
观测分子量 | 120-140 kDa |
GenBank蛋白编号 | BC052985 |
基因名称 | BMPR2 |
Gene ID (NCBI) | 659 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q13873 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. The dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form, and 150 kD dimer.