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BRE Monoclonal antibody, PBS Only

BRE Monoclonal Antibody for WB,Indirect ELISA,IHC,IF

Host / Isotype

Mouse / IgG2a

Reactivity

human, rat, mouse

Applications

WB,Indirect ELISA,IHC,IF

Conjugate

Unconjugated

CloneNo.

2E5A5

Cat No : 66356-1-PBS

Print datasheet

Synonyms

BABAM2, BRCA1 A complex subunit BRE, BRCC4, BRCC45, BRE, BRISC and BRCA1-A complex member 2

验证数据展示

  • WB analysis of fetal human brain using 66356-1-Ig (same clone as 66356-1-PBS)

    WB analysis of fetal human brain using 66356-1-Ig (same clone as 66356-1-PBS)

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66356-1-Ig (BRE Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    IF Staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using BRE antibody (66356-1-Ig, Clone: 2E5A5 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66356-1-Ig (BRE Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66356-1-Ig (BRE Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

产品信息

66356-1-PBS targets BRE in WB, IF, IHC, Indirect ELISA applications and shows reactivity with human, rat, mouse samples.

Tested Applications WB,Indirect ELISA,IHC,IF Application Description
Tested Reactivity human, rat, mouse
Immunogen BRE fusion protein Ag2256 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name brain and reproductive organ-expressed (TNFRSF1A modulator)
Synonyms BABAM2, BRCA1 A complex subunit BRE, BRCC4, BRCC45, BRE, BRISC and BRCA1-A complex member 2
Calculated Molecular Weight 383 aa, 44 kDa
Observed Molecular Weight 42-47 kDa
GenBank Accession NumberBC001251
Gene Symbol BRE
Gene ID (NCBI) 9577
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NXR7
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

BRE, also named as BRCC45, is a death receptor-associated antiapoptotic protein, which is also involved in DNA-damage repair, and K63-specific deubiquitination. BRE and its XIAP-sustaining mechanism could represent novel targets for anti-cancer therapy. BRE may regulate TNF-alpha signaling through its interactions with TNFRSF1A. It plays a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. BRE gene has four isoforms with MW 42-47 kDa.