• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

BRE Monoclonal antibody, PBS Only

BRE Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, rat, mouse

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E5A5

Cat no : 66356-1-PBS

Print datasheet

Synonyms

BABAM2, BRCA1 A complex subunit BRE, BRCC4, BRCC45, BRE, BRISC and BRCA1-A complex member 2

验证数据展示

  • WB analysis of fetal human brain using 66356-1-Ig (same clone as 66356-1-PBS)

    WB analysis of fetal human brain using 66356-1-Ig (same clone as 66356-1-PBS)

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66356-1-Ig (BRE Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    IF Staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using BRE antibody (66356-1-Ig, Clone: 2E5A5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66356-1-Ig (BRE Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    IHC staining of mouse brain using 66356-1-Ig (same clone as 66356-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66356-1-Ig (BRE Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66356-1-PBS in a different storage buffer formulation.

产品信息

66356-1-PBS targets BRE in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, rat, mouse samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, rat, mouse
Immunogen BRE fusion protein Ag2256 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name brain and reproductive organ-expressed (TNFRSF1A modulator)
Synonyms BABAM2, BRCA1 A complex subunit BRE, BRCC4, BRCC45, BRE, BRISC and BRCA1-A complex member 2
Calculated Molecular Weight 383 aa, 44 kDa
Observed Molecular Weight 42-47 kDa
GenBank Accession NumberBC001251
Gene Symbol BRE
Gene ID (NCBI) 9577
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NXR7
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BRE, also named as BRCC45, is a death receptor-associated antiapoptotic protein, which is also involved in DNA-damage repair, and K63-specific deubiquitination. BRE and its XIAP-sustaining mechanism could represent novel targets for anti-cancer therapy. BRE may regulate TNF-alpha signaling through its interactions with TNFRSF1A. It plays a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. BRE gene has four isoforms with MW 42-47 kDa.