验证数据展示
经过测试的应用
Positive IF-P detected in | human prostate cancer tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-66207 targets Beta-2-Microglobulin in IF-P applications and shows reactivity with human samples.
经测试应用 | IF-P Application Description |
经测试反应性 | human |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | beta-2-microglobulin |
别名 | B2M, beta 2 microglobulin, Beta-2-Microglobulin, HDCMA22P |
计算分子量 | 14 kDa |
观测分子量 | 13 kDa |
GenBank蛋白编号 | BC032589 |
基因名称 | B2M |
Gene ID (NCBI) | 567 |
ENSEMBL Gene ID | ENSG00000166710 |
RRID | AB_2919298 |
偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
最大激发/发射波长 | 493 nm / 522 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P61769 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 Beta-2-Microglobulin antibody CL488-66207 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |