验证数据展示
产品信息
68502-1-PBS targets Beta Arrestin 2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | Beta Arrestin 2 fusion protein Ag29807 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | arrestin, beta 2 |
Synonyms | ARRB2, β-Arrestin 2, BARR2, Arrestin beta-2, ARR2 |
Calculated Molecular Weight | 46 kDa |
Observed Molecular Weight | 50 kDa |
GenBank Accession Number | BC007427 |
Gene Symbol | Beta Arrestin 2 |
Gene ID (NCBI) | 409 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P32121 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Beta Arrestin 2 is a member of arrestin/beta-arrestin protein family, which are expressed at high levels in the central nervous system (CNS) and play a critical role in the regulation of G-protein coupled receptors (GPCRs) including MOR. Beta Arrestin 2 is an adaptor protein that is important for the regulation of receptors belonging to both dopaminergic and opioid systems. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.