验证数据展示
产品信息
24820-1-PBS targets C1RL in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | C1RL fusion protein Ag20324 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | complement component 1, r subcomponent-like |
别名 | |
计算分子量 | 487 aa, 53 kDa |
观测分子量 | 70 kDa |
GenBank蛋白编号 | BC156780 |
基因名称 | C1RL |
Gene ID (NCBI) | 51279 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9NZP8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
C1r-like serine protease analog protein (CLSPa), also named as CIRL contains a CUB domain and a serine protease domain, possessing characteristic catalytic triad. C1RL is upregulated in glioblastoma (GBM) and has been proved to be a prognostic marker in hepatocellular carcinoma and renal cell cancer (PMID: 32993564). C1RL has a calculated molecular weight of 53 kDa, and this antibody can detect a band at 70 kDa due to possible N-glycosylation (PMID: 15358180).