验证数据展示
产品信息
66608-1-PBS targets CA3 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Applications | WB, IHC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat, pig, rabbit |
Immunogen | CA3 fusion protein Ag7513 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | carbonic anhydrase III, muscle specific |
Synonyms | Carbonic anhydrase III, Car3, CA-III, CAIII, CA III |
Calculated Molecular Weight | 29 kDa |
Observed Molecular Weight | 29 kDa |
GenBank Accession Number | BC004897 |
Gene Symbol | CA3 |
Gene ID (NCBI) | 761 |
RRID | AB_2881968 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P07451 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Carbonic anhydrase III (CA3), which belongs to the alpha-carbonic anhydrase family, is a cytoplasmic enzyme that exhibits a relatively low carbon dioxide hydratase activity. It is expressed at a very high level in skeletal muscle, where physical exercise has been shown to increase free radical production. In addition to its carbon dioxide hydratase activity, CA3 has been demonstrated to have a carboxyl esterase activity and phosphatase activity, which suggests that it is a tyrosine phosphatase (PMID: 10064618). CA3 was found to be localized in Type-I muscle fibers and could be used as a marker for abnormal Type-I muscle fibers in several neuromuscular diseases (PMID: 6221502).