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Host
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of RAW 264.7 using 66353-1-Ig (same clone as 66353-1-PBS)

    WB analysis of RAW 264.7 using 66353-1-Ig (same clone as 66353-1-PBS)

    RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 66353-1-Ig (CBLB Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66353-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 66353-1-Ig (same clone as 66353-1-PBS)

    IHC staining of human heart using 66353-1-Ig (same clone as 66353-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 66353-1-Ig (CBLB Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66353-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 66353-1-Ig (same clone as 66353-1-PBS)

    IHC staining of human heart using 66353-1-Ig (same clone as 66353-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 66353-1-Ig (CBLB Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66353-1-PBS in a different storage buffer formulation.

  • IF Staining of RAW 264.7 using 66353-1-Ig (same clone as 66353-1-PBS)

    IF Staining of RAW 264.7 using 66353-1-Ig (same clone as 66353-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol ) fixed RAW 264.7 cells using 66353-1-Ig(CBLB antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66353-1-PBS in a different storage buffer formulation.

CBLB Monoclonal antibody, PBS Only

CBLB Monoclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 66353-1-PBS

产品说明书

CloneNo. 2D3A2

宿主/亚型

Mouse / IgG3

种属反应性

human, mouse, pig, rat

应用

WB, IHC, IF/ICC, ELISA

别名

CBLB, Nbla00127, RING finger protein 56, RNF56, SH3 binding protein CBL B

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66353-1-PBS targets CBLB in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse, pig, rat samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
经测试反应性 human, mouse, pig, rat
免疫原 CBLB fusion protein Ag18757 种属同源性预测
宿主/亚型 Mouse / IgG3
抗体类别 Monoclonal
产品类型 Antibody
全称 Cas-Br-M (murine) ecotropic retroviral transforming sequence b
别名 CBLB, Nbla00127, RING finger protein 56, RNF56, SH3 binding protein CBL B
计算分子量 982 aa, 109 kDa
观测分子量 110 kDa
GenBank蛋白编号BC032851
基因名称 CBLB
Gene ID (NCBI) 868
RRIDAB_2881733
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13191
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CBLB(E3 ubiquitin-protein ligase CBL-B) is also known as RNF56 and plays a necessary role to prevent the inappropriate activation of NF-B in response to lipopolysaccharide and to polymicrobial sepsis. CBLB can be phosphorylated on tyrosine and serine residues upon TCR or BCR activation, and upon various types of cell stimulation.. It also has a crucial role in the prevention of chronic inflammation and autoimmunity. This protein has 3 isoforms produced by alternative splicing.