验证数据展示
产品信息
24449-1-PBS targets CCBE1 in IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | CCBE1 fusion protein Ag19686 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | collagen and calcium binding EGF domains 1 |
别名 | |
计算分子量 | 406 aa, 44 kDa |
GenBank蛋白编号 | BC046645 |
基因名称 | CCBE1 |
Gene ID (NCBI) | 147372 |
RRID | AB_2879553 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q6UXH8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).