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CCBE1 Polyclonal antibody, PBS Only

CCBE1 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 24449-1-PBS

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Synonyms

验证数据展示

  • IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 24449-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    IHC staining of human kidney using 24449-1-AP (same clone as 24449-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 24449-1-PBS in a different storage buffer formulation.

产品信息

24449-1-PBS targets CCBE1 in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CCBE1 fusion protein Ag19686 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name collagen and calcium binding EGF domains 1
Synonyms
Calculated Molecular Weight 406 aa, 44 kDa
GenBank Accession NumberBC046645
Gene Symbol CCBE1
Gene ID (NCBI) 147372
RRIDAB_2879553
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6UXH8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).