验证数据展示
产品信息
21869-1-PBS targets CCHCR1 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | CCHCR1 fusion protein Ag16141 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | coiled-coil alpha-helical rod protein 1 |
别名 | |
计算分子量 | 871 aa, 99 kDa |
观测分子量 | 85 kDa |
GenBank蛋白编号 | BC110534 |
基因名称 | CCHCR1 |
Gene ID (NCBI) | 54535 |
RRID | AB_2878932 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q8TD31 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCHCR1, also named as C6orf18 or Putative gene 8 protein, is a 782 amino acid protein, which is a nuclear protein abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and to a lesser extent in lung and placenta. HCR is overexpressed in keratinocytes of psoriatic lesions. HCR is associated with susceptibility to psoriasis, a chronic inflammatory dermatosis that affects approximately 2% of the population. CCHCR1 may be a regulator of keratinocyte proliferation or differentiation.