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CCR5 Recombinant antibody, PBS Only

CCR5 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230266A6

Cat no : 82942-1-PBS

Print datasheet

Synonyms

C-C CKR-5, CC CKR 5, C-C chemokine receptor type 5, C C CKR 5, C C chemokine receptor type 5

验证数据展示

  • WB analysis using 82942-1-RR (same clone as 82942-1-PBS)

    WB analysis using 82942-1-RR (same clone as 82942-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82942-1-RR (CCR5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82942-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82942-1-PBS

    Affinity and Kinetic Characterization of 82942-1-PBS

    Biolayer interferometry (BLl) kinetic assays of 82942-1-RR against Human CCR5 were performed. The affinity constant is 0.921 nM.

产品信息

82942-1-PBS targets CCR5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse
Immunogen CCR5 fusion protein Ag11493 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name chemokine (C-C motif) receptor 5
Synonyms C-C CKR-5, CC CKR 5, C-C chemokine receptor type 5, C C CKR 5, C C chemokine receptor type 5
Calculated Molecular Weight 352 aa, 41 kDa
Observed Molecular Weight45 kDa
GenBank Accession NumberBC038398
Gene Symbol CCR5
Gene ID (NCBI) 1234
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP51681
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CCR5 (also known as CD195) is a member of the beta chemokine receptor family. This protein is expressed by T cells and macrophages and is known to be an important co-receptor for macrophage-tropic viruses, including HIV, to enter host cells. The natural chemokine ligands that bind to CCR5 include MIP-1-alpha, MIP-1-beta, MCP-2, and RANTES.