Anti-Mouse CD107b / LAMP2 (ABL-93)
CD107b / LAMP2 Monoclonal Antibody for IF/ICC, FC (Intra)
Host / Isotype
Rat / IgG2a, kappa
Reactivity
Mouse and More (1)
Applications
IF/ICC, FC (Intra) and More (1)
Conjugate
Unconjugated
CloneNo.
ABL-93
验证数据展示
经过测试的应用
| Positive IF/ICC detected in | NIH/3T3 cells |
| Positive FC (Intra) detected in | NIH/3T3 cells |
| Positive FC detected in | NIH/3T3 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IF | See 1 publications below |
产品信息
65052-1-Ig targets CD107b / LAMP2 in IF/ICC, FC (Intra) applications and shows reactivity with Mouse samples.
| Tested Applications | IF/ICC, FC (Intra) Application Description |
| Cited Applications | IF |
| Tested Reactivity | Mouse |
| Cited Reactivity | mouse |
| Immunogen | Glycoproteins purified from BALB/c mouse embryo 3T3 cell line 种属同源性预测 |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | lysosomal-associated membrane protein 2 |
| Synonyms | CD107b, Lamp2, Mac3, Lamp 2, ABL-93 |
| GenBank Accession Number | BC138718 |
| Gene Symbol | CD107b |
| Gene ID (NCBI) | 16784 |
| RRID | AB_2881468 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | P17047 |
| Storage Buffer | PBS with 0.09% sodium azide. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis (PMID 9426697).
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CD107b / LAMP2 antibody 65052-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Cell Rep Med Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing |
