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CD11c/Integrin alpha X Recombinant antibody, PBS Only

CD11c/Integrin alpha X Recombinant Antibody for Indirect ELISA,IHC,IF

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

Indirect ELISA,IHC,IF

Conjugate

Unconjugated

CloneNo.

5O17

Cat No : 81853-1-PBS

Print datasheet

Synonyms

CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6

验证数据展示

  • IHC staining of human tonsillitis using 81853-1-RR (same clone as 81853-1-PBS)

    IHC staining of human tonsillitis using 81853-1-RR (same clone as 81853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 81853-1-RR (CD11c/Integrin alpha X antibody) at dilution of 1:1500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81853-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD11c antibody included
  • IHC staining of human tonsillitis using 81853-1-RR (same clone as 81853-1-PBS)

    IHC staining of human tonsillitis using 81853-1-RR (same clone as 81853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 81853-1-RR (CD11c/Integrin alpha X antibody) at dilution of 1:1500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81853-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD11c antibody included
  • IF Staining of THP-1 using 81853-1-RR (same clone as 81853-1-PBS)

    IF Staining of THP-1 using 81853-1-RR (same clone as 81853-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CD11c/Integrin alpha X antibody (81853-1-RR, Clone: 5O17 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 81853-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CD11c Ready-To-Use IHC Kit. CD11c primary antibody included.

产品信息

81853-1-PBS targets CD11c/Integrin alpha X in IF, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications Indirect ELISA,IHC,IF Application Description
Tested Reactivity Human
Immunogen CD11c/Integrin alpha X fusion protein Ag11380 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name integrin, alpha X (complement component 3 receptor 4 subunit)
Synonyms CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6
Calculated Molecular Weight 1169 aa, 129 kDa
GenBank Accession NumberBC038237
Gene Symbol ITGAX
Gene ID (NCBI) 3687
ENSEMBL Gene IDENSG00000140678
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP20702
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).