CD11c/Integrin alpha X Recombinant antibody

CD11c/Integrin alpha X Uni-rAbTM Recombinant Antibody for IHC, IF/ICC, ELISA
Cat No. 81853-1-RR

产品说明书

CloneNo. 5O17

宿主/亚型

Rabbit / IgG

种属反应性

human and More (1)

应用

IHC, IF/ICC, ELISA and More (1)

CD11c, ITGAX, Integrin alpha-X, Integrin alpha X, CD11 antigen-like family member C

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
CoraLite®594
规格: 

-/ -


经过测试的应用

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inPMA treated THP-1 cells
Planning an IHC experiment? We recommend our IHCeasy CD11c Ready-To-Use IHC Kit. CD11c primary antibody included.

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:500-1:2000
Immunofluorescence (IF)/ICCIF/ICC : 1:125-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 2 publications below

产品信息

81853-1-RR targets CD11c/Integrin alpha X in IHC, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, ELISA Application Description
文献引用应用IF
经测试反应性 human
文献引用反应性rat
免疫原 CD11c/Integrin alpha X fusion protein Ag11380 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, alpha X (complement component 3 receptor 4 subunit)
别名 CD11c, ITGAX, Integrin alpha-X, Integrin alpha X, CD11 antigen-like family member C
计算分子量 1169 aa, 129 kDa
GenBank蛋白编号BC038237
基因名称 CD11c
Gene ID (NCBI) 3687
ENSEMBL Gene IDENSG00000140678
RRIDAB_2935585
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP20702
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

实验方案

Product Specific Protocols
IHC protocol for CD11c/Integrin alpha X antibody 81853-1-RRDownload protocol
IF protocol for CD11c/Integrin alpha X antibody 81853-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
ratIF

FASEB J

Metformin switches cell death modes to soothe the apical periodontitis via ZBP1

Authors - Hui Liu
ratIF

Eur J Cardiothorac Surg

Colchicine prevents perioperative myocardial injury in cardiac surgery by inhibiting the formation of neutrophil extracellular traps: evidence from rat models

Authors - Hao-Dong Pan
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