• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

CD122/IL-2RB Recombinant antibody, PBS Only

CD122/IL-2RB Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241677C9

Cat no : 84389-2-PBS

Print datasheet

Synonyms

IL2RB, IL 2RB, IL 2R subunit beta, IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta

验证数据展示

  • WB analysis using 84389-2-RR (same clone as 84389-2-PBS)

    WB analysis using 84389-2-RR (same clone as 84389-2-PBS)

    NK-92 cells were subjected to SDS PAGE followed by western blot with 84389-2-RR (CD122/IL-2RB antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84389-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84389-2-RR

    Affinity and Kinetic Characterization of 84389-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84389-2-RR against Human CD122/IL-2RB were performed. The affinity constant is 32.2 nM.

产品信息

84389-2-PBS targets CD122/IL-2RB in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name interleukin 2 receptor, beta
Synonyms IL2RB, IL 2RB, IL 2R subunit beta, IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta
Calculated Molecular Weight 551 aa, 61 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC025691
Gene Symbol IL2RB
Gene ID (NCBI) 3560
ENSEMBL Gene IDENSG00000100385
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP14784
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.