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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98037-2-RR (same clone as 98037-2-PBS)

    FC experiment of human peripheral blood leukocytes using 98037-2-RR (same clone as 98037-2-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human Thrombomodulin Rabbit Recombinant Antibody (98037-2-RR, Clone: 240365H3) or 0.25 ug Control Antibody, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98037-2-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98037-2-RR (same clone as 98037-2-PBS)

    FC experiment of human peripheral blood leukocytes using 98037-2-RR (same clone as 98037-2-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human Thrombomodulin Rabbit Recombinant Antibody (98037-2-RR, Clone: 240365H3) (red) or 0.25 ug Control Antibody (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98037-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98037-2-RR

    Affinity and Kinetic Characterization of 98037-2-RR

    Biolayer interferometry (BLl) kinetic assays of 98037-2-RR against Human CD141/Thrombomodulin were performed. The affinity constant is 0.684 nM.

Anti-Human CD141/Thrombomodulin Rabbit Recombinant Antibody, PBS Only

CD141/Thrombomodulin Uni-rAbTM Recombinant Antibody for FC
Cat No. 98037-2-PBS

产品说明书

CloneNo. 240365H3

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

THBD, Thrombomodulin, THRM, Fetomodulin, CD141

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CD141/Thrombomodulin Ready-To-Use IHC Kit. CD141/Thrombomodulin primary antibody included.

产品信息

98037-2-PBS targets CD141/Thrombomodulin in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 thrombomodulin
别名 THBD, Thrombomodulin, THRM, Fetomodulin, CD141
计算分子量60 kDa
GenBank蛋白编号NM_000361.3
基因名称 THBD
Gene ID (NCBI) 7056
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP07204
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Thrombomodulin, also known as CD141, is an endothelial cell surface glycoprotein that forms a 1:1 complex with the coagulation factor thrombin and plays an important role as a natural anticoagulant. Thrombomodulin serves to convert thrombin from a procoagulant protein into the activator for protein C. Once converted to activated protein C (APC), this protein serves as a major anticoagulant in blood (PMID: 2827310). Thrombomodulin is also located in other cells (keratinocytes, osteoblasts, macrophages,...) where it might be involved in cell differentiation or in inflammation (PMID: 9814688). In humans, thrombomodulin is encoded by the THBD gene. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. Thrombomodulin is glycosylated and has an apparent molecular weight of 75 to 110 kDa (PMID: 1650405; 2827310).