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Host
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Species Reactivity
0
Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • IF Staining of HeLa using 82909-1-RR (same clone as 82909-1-PBS)

    IF Staining of HeLa using 82909-1-RR (same clone as 82909-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CD147 antibody (82909-1-RR, Clone: 230046C1 ) at dilution of 1:1000 and Multi-rAb CoraLite ® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM004). This data was developed using the same antibody clone with 82909-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 82909-1-RR (same clone as 82909-1-PBS)

    IF Staining of MCF-7 using 82909-1-RR (same clone as 82909-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using CD147 antibody (82909-1-RR, Clone: 230046C1 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 82909-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82909-1-RR

    Affinity and Kinetic Characterization of 82909-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82909-1-RR against Human CD147 were performed. The affinity constant is 4.68 nM.

CD147 Recombinant antibody, PBS Only

CD147 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Cat No. 82909-1-PBS

产品说明书

CloneNo. 230046C1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, Indirect ELISA

别名

230046C1, 5F7, Basigin, BSG, Collagenase stimulatory factor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CD147/BSG Ready-To-Use IHC Kit. CD147/BSG primary antibody included.

产品信息

82909-1-PBS targets CD147 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 basigin (Ok blood group)
别名 230046C1, 5F7, Basigin, BSG, Collagenase stimulatory factor
计算分子量 385 aa, 42 kDa
GenBank蛋白编号BC009040
基因名称 CD147
Gene ID (NCBI) 682
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP35613
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD147, also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 7812975). The molecule is composed of an intracellular portion, an extracellular portion and a single transmembrane region. CD147 is expressed on a variety of cell types (e.g., hematopoietic, epithelial, and endothelial cells) and at varying levels (PMID: 32968061). Increased expression of CD147 occurs in many tumors. CD147 is a pleiotropic molecule that plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development (PMID: 17945211). CD147 has been identified as a receptor essential for erythrocyte invasion by Plasmodium falciparum (PMID: 22080952). It has been reported that spike protein of SARS-CoV-2 binds to CD147 on host cells, thereby mediating the viral invasion (Wang, Ke, et al, BioRxiv, 2020).