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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • FC experiment of human PBMCs using 65632-1-MR (same clone as 65632-1-PBS)

    FC experiment of human PBMCs using 65632-1-MR (same clone as 65632-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD155/PVR (SKII.4) Mouse IgG2a Recombinant Antibody (65632-1-MR, Clone: SKII.4) or Mouse IgG2a Isotype Control, and PE-conjugated Goat Anti-Mouse IgG. Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed. Monocytes were gated. This data was developed using the same antibody clone with 65632-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65632-1-MR (same clone as 65632-1-PBS)

    FC experiment of human PBMCs using 65632-1-MR (same clone as 65632-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD155/PVR (SKII.4) Mouse IgG2a Recombinant Antibody (65632-1-MR, Clone: SKII.4) (red) or Mouse IgG2a Isotype Control (blue), and PE-conjugated Goat Anti-Mouse IgG. Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed. Monocytes were gated. This data was developed using the same antibody clone with 65632-1-PBS in a different storage buffer formulation.

Anti-Human CD155/PVR (SKII.4) Mouse IgG2a Recombinant Antibody, PBS Only

CD155/PVR Recombinant Antibody for FC
Cat No. 65632-1-PBS

产品说明书

CloneNo. SKII.4

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

PVR, Nectin like protein 5, NECL-5, NECL5, Necl 5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PVR Ready-To-Use IHC Kit. PVR primary antibody included.

产品信息

65632-1-PBS targets CD155/PVR in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 SK-N-AS human neuroblastoma cells 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 poliovirus receptor
别名 PVR, Nectin like protein 5, NECL-5, NECL5, Necl 5
计算分子量 45 kDa
GenBank蛋白编号BC015542
基因名称 CD155/PVR
Gene ID (NCBI) 5817
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD155, also known as PVR, is a type I transmembrane glycoprotein in the immunoglobulin superfamily. It contains three extracellular immunoglobulin-like domains, D1-D3, of which D1 is recognized by the virus. Mature human CD155 consists of a 323 amino acid extracellular domain with one N-terminal V-type and two C2-type Ig-like domains, a 24 amino acid transmembrane segment, and a 50 amino acid cytoplasmic tail. CD155 is thought to play a role in adhesion by interaction with the ECM component vitronectin as well as a role in NK killing of tumor cells. CD155 binds to two receptors of NK cells, CD96 and CD226, and accumulates at cell-cell contact sites, leading to the formation of mature immune synapses between NK cells and target cells. CD155 serves as the entry receptor for poliovirus and thereby mediates human susceptibility to poliovirus infection.