验证数据展示
产品信息
28838-1-PBS targets CD1c in IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | CD1c fusion protein Ag29830 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | CD1c molecule |
别名 | |
计算分子量 | 333 aa, 38 kDa |
GenBank蛋白编号 | BC126467 |
基因名称 | CD1C |
Gene ID (NCBI) | 911 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P29017 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD1c molecule (CD1c, also known as R7, CD1, CD1A, and BDCA1) is a member of the CD1 family of transmembrane glycoproteins, which synthesizes in the endoplasmic reticulum and expresses on the monocytes, marginal zone B cells in lymph nodes as well as peripheral blood (PMID: 23468110). The CD1 proteins belong to the family of major histocompatibility complex (MHC) class I-like proteins that present lipid-based antigens to T cells (PMID: 15032598; 23127489). CD1c shows interaction with both αβ or γδ T cells and mediates T cell responses against mycobacterium tuberculosis (PMID: 10727456; 10786796).