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验证数据展示

  • WB analysis of fetal human brain using 66282-1-Ig (same clone as 66282-1-PBS)

    WB analysis of fetal human brain using 66282-1-Ig (same clone as 66282-1-PBS)

    Untreated and PNGase F-treated lysates of fetal human brain tissue and human spleen tissue were subjected to SDS PAGE followed by western blot with 66282-1-Ig (CD200 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. PNGase F was obtained from Atagenix (cat.NO. ata808). This data was developed using the same antibody clone with 66282-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66282-1-Ig (CD200 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66282-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    IHC staining of human tonsillitis using 66282-1-Ig (same clone as 66282-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66282-1-Ig (CD200 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66282-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CD200 Monoclonal antibody, PBS Only

CD200 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66282-1-PBS

产品说明书

CloneNo. 5F3D6

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

CD200, CD200 molecule, MOX1, MOX2, MRC, OX 2, OX 2 membrane glycoprotein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66282-1-PBS targets CD200 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD200 fusion protein Ag5045 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD200 molecule
别名 CD200, CD200 molecule, MOX1, MOX2, MRC, OX 2, OX 2 membrane glycoprotein
计算分子量 269 aa, 30 kDa
观测分子量 40-50 kDa
GenBank蛋白编号BC022522
基因名称 CD200
Gene ID (NCBI) 4345
RRIDAB_2881665
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP41217
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).