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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse splenocytes using 98039-1-RR (same clone as 98039-1-PBS)

    FC experiment of mouse splenocytes using 98039-1-RR (same clone as 98039-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD200 Rabbit Recombinant Antibody (98039-1-RR, Clone: 240391A6) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD45R (B220) (RA3-6B2) (CL647-65139, Clone: RA3-6B2). Cells were not fixed. This data was developed using the same antibody clone with 98039-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98039-1-RR (same clone as 98039-1-PBS)

    FC experiment of mouse splenocytes using 98039-1-RR (same clone as 98039-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD200 Rabbit Recombinant Antibody (98039-1-RR, Clone: 240391A6) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98039-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98039-1-RR

    Affinity and Kinetic Characterization of 98039-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98039-1-RR against Mouse CD200 were performed. The affinity constant is 0.879 nM.

Anti-Mouse CD200 Rabbit Recombinant Antibody, PBS Only

CD200 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98039-1-PBS

产品说明书

CloneNo. 240391A6

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

OX2, Mox2, CD200 antigen, 240391A6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98039-1-PBS targets CD200 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD200 antigen
别名 OX2, Mox2, CD200 antigen, 240391A6
计算分子量31 kDa
基因名称 Cd200
Gene ID (NCBI) 17470
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO54901
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).