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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 98254-1-RR (same clone as 98254-1-PBS)

    FC experiment of human PBMCs using 98254-1-RR (same clone as 98254-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD268/BAFF-R Rabbit Recombinant Antibody (98254-1-RR, Clone: 242003A1) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD19. Cells were not fixed. This data was developed using the same antibody clone with 98254-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98254-1-RR (same clone as 98254-1-PBS)

    FC experiment of human PBMCs using 98254-1-RR (same clone as 98254-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD268/BAFF-R Rabbit Recombinant Antibody (98254-1-RR, Clone: 242003A1)(red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98254-1-PBS in a different storage buffer formulation.

Anti-Human CD268/BAFF-R Rabbit Recombinant Antibody, PBS Only

CD268/BAFF-R Uni-rAbTM Recombinant Antibody for FC
Cat No. 98254-1-PBS

产品说明书

CloneNo. 242003A1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TNFRSF13C Ready-To-Use IHC Kit. TNFRSF13C primary antibody included.

产品信息

98254-1-PBS targets CD268/BAFF-R in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 13C
别名 TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor
计算分子量 184 aa, 19 kDa
GenBank蛋白编号BC105123
基因名称 TNFRSF13C
Gene ID (NCBI) 115650
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ96RJ3
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).