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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 25323-1-AP (same clone as 25323-1-PBS)

    WB analysis using 25323-1-AP (same clone as 25323-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25323-1-AP (CD32A/C antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25323-1-PBS in a different storage buffer formulation.

CD32A/C Polyclonal antibody, PBS Only

CD32A/C Polyclonal Antibody for WB, Indirect ELISA
Cat No. 25323-1-PBS

Print datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

25323-1-PBS targets CD32A/C in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CD32A/C fusion protein Ag18123 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name Fc fragment of IgG, low affinity IIc, receptor for (CD32)
Synonyms
Calculated Molecular Weight 323 aa, 36 kDa
Observed Molecular Weight40 kDa
GenBank Accession NumberBC137397
Gene Symbol CD32A/C
Gene ID (NCBI) 9103
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP31995
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IgG Fc receptors (FcγRs) play important roles in immune responses. The low-affinity IgG Fc receptor, FcγRII (CD32), consists of a family of primarily cell membrane receptor proteins: CD32A, CD32B, and CD32C. They are encoded by the mRNA splice variants of three highly related genes: FCGR2A, FCGR2B, and FCGR2C (PMID: 30941127). CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. This antibody raised against 254-323 aa of human CD32C (FCGR2C) can recognize both CD32A and CD32C forms.