CD38 Recombinant antibody

CD38 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Mouse / IgG

Reactivity

rabbit

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

241357C3

Cat no : 84689-1-MR

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Synonyms

Cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase 1, ADPRC 1, 2'-phospho-ADP-ribosyl cyclase



经过测试的应用

Positive WB detected inrabbit splenocytes cells, rabbit serum

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 84689-1-MR is CD38 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Tested Reactivity rabbit
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Mouse / IgG
Class Recombinant
Type Antibody
Full Name CD38
Synonyms Cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase 1, ADPRC 1, 2'-phospho-ADP-ribosyl cyclase
Observed Molecular Weight45-50 kDa
Gene Symbol CD38
Gene ID (NCBI) 100009409
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9MZ03
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

实验方案

Product Specific Protocols
WB protocol for CD38 antibody 84689-1-MRDownload protocol
Standard Protocols
Click here to view our Standard Protocols