验证数据展示
产品信息
84689-1-PBS targets CD38 in WB, Indirect ELISA applications and shows reactivity with rabbit samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | rabbit |
| Immunogen | Fusion Protein 种属同源性预测 |
| Host / Isotype | Mouse / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | CD38 |
| Synonyms | 241357C3 |
| Observed Molecular Weight | 45-50 kDa |
| Gene Symbol | CD38 |
| Gene ID (NCBI) | 100009409 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q9MZ03 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).
