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Anti-Human CD38 Rabbit Recombinant Antibody, PBS Only

CD38 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241246F9

Cat no : 98148-1-PBS

Print datasheet

Synonyms

ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase

验证数据展示

  • FC experiment of human PBMCs using 98148-1-RR (same clone as 98148-1-PBS)

    FC experiment of human PBMCs using 98148-1-RR (same clone as 98148-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD38 Rabbit Recombinant Antibody (98148-1-RR, Clone:241246F9) or Isotype Control and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD14 (26IC) (APC-65246, Clone: 26IC). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98148-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98148-1-RR (same clone as 98148-1-PBS)

    FC experiment of human PBMCs using 98148-1-RR (same clone as 98148-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD38 Rabbit Recombinant Antibody (98148-1-RR, Clone:241246F9) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98148-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98148-1-RR

    Affinity and Kinetic Characterization of 98148-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98148-1-RR against Human CD38 were performed. The affinity constant is 0.669 nM.

Planning an IHC experiment? We recommend our IHCeasy CD38 Ready-To-Use IHC Kit. CD38 primary antibody included.

产品信息

The immunogen of 98148-1-PBS is CD38 Fusion Protein expressed in E. coli.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD38 molecule
Synonyms ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase
Calculated Molecular Weight 300 aa, 34 kDa
GenBank Accession NumberBC007964
Gene Symbol CD38
Gene ID (NCBI) 952
ENSEMBL Gene IDENSG00000004468
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP28907
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).