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验证数据展示

  • FC experiment of human PBMCs using 98148-1-RR

    FC experiment of human PBMCs using 98148-1-RR

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD38 Rabbit Recombinant Antibody (98148-1-RR, Clone:241246F9) or Isotype Control and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD14 (26IC) (APC-65246, Clone: 26IC). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • FC experiment of human PBMCs using 98148-1-RR

    FC experiment of human PBMCs using 98148-1-RR

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD38 Rabbit Recombinant Antibody (98148-1-RR, Clone:241246F9) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

  • Affinity and Kinetic Characterization of 98148-1-RR

    Affinity and Kinetic Characterization of 98148-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98148-1-RR against Human CD38 were performed. The affinity constant is 0.669 nM.

Anti-Human CD38 Rabbit Recombinant Antibody

CD38 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98148-1-RR

产品说明书

CloneNo. 241246F9

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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经过测试的应用

Positive FC detected inhuman PBMCs
Planning an IHC experiment? We recommend our IHCeasy CD38 Ready-To-Use IHC Kit. CD38 primary antibody included.

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98148-1-RR targets CD38 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD38 molecule
别名 ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase
计算分子量 300 aa, 34 kDa
GenBank蛋白编号BC007964
基因名称 CD38
Gene ID (NCBI) 952
ENSEMBL Gene IDENSG00000004468
RRIDAB_3672293
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP28907
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

实验方案

Product Specific Protocols
FC protocol for CD38 antibody 98148-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols