PE Anti-Mouse CD40 (1C10)
CD40 Monoclonal Antibody for FC
Host / Isotype
Rat / IgG2a, kappa
Reactivity
Mouse
Applications
FC
Conjugate
PE Fluorescent Dye
CloneNo.
1C10
验证数据展示
经过测试的应用
Positive FC detected in | mouse splenocytes |
推荐稀释比
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
PE-65062 targets CD40 in FC applications and shows reactivity with Mouse samples.
Tested Applications | FC Application Description |
Tested Reactivity | Mouse |
Immunogen | sCD40 种属同源性预测 |
Host / Isotype | Rat / IgG2a, kappa |
Class | Monoclonal |
Type | Antibody |
Full Name | CD40 antigen |
Synonyms | AI326936, Bp50, Cd40, CD40 antigen, GP39, HIGM1, IGM, IMD3, p50, T BAM, Tnfrsf5 |
GenBank Accession Number | BC029254 |
Gene Symbol | Cd40 |
Gene ID (NCBI) | 21939 |
RRID | AB_2883859 |
Conjugate | PE Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 496 nm, 565 nm / 578 nm |
Form | Liquid |
Purification Method | Affinity purification |
UNIPROT ID | P27512 |
Storage Buffer | PBS with 0.1% sodium azide and a stabilizer. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497).
实验方案
Product Specific Protocols | |
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FC protocol for PE CD40 antibody PE-65062 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |