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Anti-Human CD41a (HIP8)

CD41a Monoclonal Antibody for FC

Host / Isotype

Mouse / Mouse IgG1

Reactivity

Non-human primates, Human

Applications

FC

Conjugate

Unconjugated

CloneNo.

HIP8

Cat No : 65173-1-Ig

Print datasheet

Synonyms

CD41, CD41a, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HIP8, HPA3, Integrin alpha IIb, ITGA2B, ITGAB

验证数据展示

  • FC experiment of human peripheral blood platelets using 65173-1-Ig

    FC experiment of human peripheral blood platelets using 65173-1-Ig

    1X10^6 human peripheral blood platelets were surface stained with 0.40 ug Purified Anti-Human CD41a (65173-1-Ig, Clone:HIP8) (red) or 0.40 ug Mouse IgG1 Isotype Control (blue) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) with dilution 1:1000. Cells were not fixed.

经过测试的应用

Positive FC detected inHuman peripheral blood platelets

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65173-1-Ig targets CD41a in FC applications and shows reactivity with Non-human primates, Human samples.

Tested Applications FC
Tested Reactivity Non-human primates, Human
Immunogen N/A 种属同源性预测
Host / Isotype Mouse / Mouse IgG1
Class Monoclonal
Type Antibody
Full Name integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyms CD41, CD41a, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HIP8, HPA3, Integrin alpha IIb, ITGA2B, ITGAB
GenBank Accession NumberBC117443
Gene Symbol ITGA2B
Gene ID (NCBI) 3674
RRIDAB_2881482
Conjugate Unconjugated
Form Liquid
Purification MethodPurified by protein-A affinity chromatography
UNIPROT IDP08514
Storage Buffer PBS with 0.1% sodium azide.
Storage ConditionsStore at 2-8°C.

背景介绍

The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands (PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits (PMID: 17543136; 20029421). In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis (PMID:19118207). Integrin alpha-IIb (ITGA2B, CD41) is expressed on platelets, megakaryocytes and some hematopoietic progenitor cells (PMID: 11934866).

实验方案

Product Specific Protocols
FC protocol for CD41a antibody 65173-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols