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验证数据展示

  • FC experiment of human peripheral blood platelets using CL488-65173

    FC experiment of human peripheral blood platelets using CL488-65173

    100 ul human platelet-rich plasma (diluted 1:2 with PBS) was surface stained with 5 ul CoraLite® Plus 488 Anti-Human CD41a (CL488-65173, Clone:HIP8) or CoraLite® Plus 488 Mouse IgG1 Isotype Control (CL488-65124). Cells were not fixed.

  • FC experiment of human peripheral blood platelets using CL488-65173

    FC experiment of human peripheral blood platelets using CL488-65173

    100 ul human platelet-rich plasma (diluted 1:2 with PBS) was surface stained with 5 ul CoraLite® Plus 488 Anti-Human CD41a (CL488-65173, Clone:HIP8) or CoraLite® Plus 488 Mouse IgG1 Isotype Control (CL488-65124). Cells were not fixed.

CoraLite® Plus 488 Anti-Human CD41a (HIP8)

CD41a Monoclonal Antibody for FC
Cat No. CL488-65173

产品说明书

CloneNo. HIP8

宿主/亚型

Mouse / IgG1, kappa

种属反应性

human, non-human primates

应用

FC

别名

GTA, GPIIb, GPalpha IIb, GP2B, CD41B

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive FC detected inhuman peripheral blood platelets
For other applications, we recommend the unconjugated version of this antibody, 65173-1-Ig

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-65173 targets CD41a in FC applications and shows reactivity with human, non-human primates samples.

经测试应用 FC Application Description
经测试反应性 human, non-human primates
免疫原 N/A 种属同源性预测
宿主/亚型 Mouse / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
别名 GTA, GPIIb, GPalpha IIb, GP2B, CD41B
GenBank蛋白编号BC117443
基因名称 CD41a
Gene ID (NCBI) 3674
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Unknow
UNIPROT IDP08514
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA.
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands (PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits (PMID: 17543136; 20029421). In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis (PMID:19118207). Integrin alpha-IIb (ITGA2B, CD41) is expressed on platelets, megakaryocytes and some hematopoietic progenitor cells (PMID: 11934866).

实验方案

Product Specific Protocols
FC protocol for CL Plus 488 CD41a antibody CL488-65173Download protocol
Standard Protocols
Click here to view our Standard Protocols