Anti-Human CD49b (AK7) Mouse IgG2a Recombinant Antibody, PBS Only

CD49b Uni-rAbTM Recombinant Antibody for FC
Cat No. 65583-1-PBS

产品说明书

CloneNo. AK7

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

ITGA2, Integrin alpha 2, GPIa, Collagen receptor, BR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

65583-1-PBS targets CD49b in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Human platelets 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
别名 ITGA2, Integrin alpha 2, GPIa, Collagen receptor, BR
计算分子量 126 kDa
GenBank蛋白编号NM_002203
基因名称 Integrin alpha 2
Gene ID (NCBI) 3673
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD49b, also known as alpha2 integrin, is a type I transmembrane glycoprotein which forms an adhesion molecule VLA-2 with beta1 integrin. CD49b is a receptor for many (extracellular) matrix and non-matrix molecules (PMID: 23847623). CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes. CD49b activation skews NK cell effector function to a phenotype that exhibits elevated IFN-γ production with a concomitant inhibition of motility and cytolytic function (PMID: 32971468, 32762681). The Anti-Human CD49b antibody, clone AK7, is derived from Human platelets.

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