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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84519-4-RR (same clone as 84519-4-PBS)

    WB analysis using 84519-4-RR (same clone as 84519-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84519-4-RR (CD55 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84519-4-PBS in a different storage buffer formulation.

Mouse CD55 Recombinant antibody, PBS Only

CD55 Recombinant Antibody for WB, Indirect ELISA
Cat No. 84519-4-PBS
CloneNo. 241808C10

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Synonyms

DAF-GPI, Daf1, Daf, Complement decay-accelerating factor, GPI-anchored, Cd55a

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

84519-4-PBS targets CD55 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity mouse
Immunogen FusionProtein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD55 antigen
Synonyms DAF-GPI, Daf1, Daf, Complement decay-accelerating factor, GPI-anchored, Cd55a
Calculated Molecular Weight43kDa
Observed Molecular Weight58-70 kDa
GenBank Accession NumberNM_010016.3
Gene Symbol CD55
Gene ID (NCBI) 13136
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ61475
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044). The observed molecular weight of mature CD55 varies between 50 to 100 kDa depending on the cell type. Different sizes of CD55 might be caused by alternative splicing or different glycosylation patterns (PMID: 29503741).