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验证数据展示

  • FC experiment of human PBMCs using 98099-1-RR (same clone as 98099-1-PBS)

    FC experiment of human PBMCs using 98099-1-RR (same clone as 98099-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD59 Rabbit Recombinant Antibody (98099-1-RR, Clone:241311A4) or Isotype Control and PE-conjugated Goat Anti-Rabbit IgG, Cells were then stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98099-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98099-1-RR (same clone as 98099-1-PBS)

    FC experiment of human PBMCs using 98099-1-RR (same clone as 98099-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD59 Rabbit Recombinant Antibody (98099-1-RR, Clone:241311A4) or Isotype Control and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98099-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98099-1-RR

    Affinity and Kinetic Characterization of 98099-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98099-1-RR against Human CD59 were performed. The affinity constant is 0.888 nM.

Anti-Human CD59 Rabbit Recombinant Antibody, PBS Only

CD59 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98099-1-PBS

产品说明书

CloneNo. 241311A4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

HRF-20, CD59 glycoprotein, CD59 antigen, CD 59, 241311A4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CD59 Ready-To-Use IHC Kit. CD59 primary antibody included.

产品信息

98099-1-PBS targets CD59 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD59 molecule, complement regulatory protein
别名 HRF-20, CD59 glycoprotein, CD59 antigen, CD 59, 241311A4
计算分子量 19 kDa
GenBank蛋白编号BC001506
基因名称 CD59
Gene ID (NCBI) 966
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP13987
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25 kDa. It acts as a determinant of proximal-distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.